Chennai: Despite all the speculation surrounding it, Kabasura Kudineer, might actually be helpful in the fight against Covid-19.
This is what is indicated by a study based on computer modelling, that is published in an open-access peer-reviewed journal.
According to S Vincent, former dean of research, Loyola College, who is a co-author of the paper, the research team selected 145 compounds found in kabasura kudineer, a poly-herbal formulation used for therapy in Siddha medicine.
The team is said to have used molecular docking technique to study how effectively the ligands of the compounds bonded with the 3C-like protease, the main protease found in the Covid-19 causing SARS-CoV-2 virus.
“Fifteen of the 145 compounds found naturally in herbs used in kabasura kudineer had greater affinity and docked effectively with the protease in SARS-CoV-2, indicating that they can potentially inhibit viral replication,” he is quoted to have said.
Stating that the method used was in the realm of bioinformatics, he said it was used to accelerate identification of the potential drug compounds, before getting into elaborate laboratory experiments and clinical trials.
The study was done in collaboration with researchers from Loyola College, Sejong University in South Korea and Mekelle University in Ethiopia, and the findings were published in the journal Frontiers in Molecular Biosciences.