Physical activity has a significant effect on brain health, and it can not only rejuvenate your brain but also prevent or delay cognitive decline that comes with ageing, according to a new study on Wednesday.
A team from the University of Queensland in Australia focussed on the expression of genes in individual cells in the brains of mice.
The results, published in the journal Aging Cell, showed that exercise has a significant impact on gene expression in microglia — the immune cells of the central nervous system that support brain function.
Importantly, the team found that exercise reverts the gene expression patterns of aged microglia to those seen in young mice.
“We were both surprised and excited about the extent to which physical activity rejuvenates and transforms the composition of immune cells within the brain, in particular the way in which it was able to reverse the negative impacts of ageing,” said Jana Vukovic, from the University of Queensland.